Product Name: Copovidone
Chemical Description: Vinylpyrrolidone with Vinyl Acetate Copolymer, PVP/VA 64 Powder
INCI/CTFA: VP/VA Copolymer
Pharmacopeia Name: Copovidone /Copovidonum
CAS NO.: 25086-89-9
Liveida ® Copovidone, an analog of povidone, is used as a tablet binder, a film-former, and as part of the matrix material in controlled-release formulations. In tableting, Copovidone can be used as a binder for direct compression and in wet granulation. Copovidone is often added to coating solutions as a film-forming agent. It provides good adhesion, elasticity, and hardness and can be used as a moisture barrier.
Liveida ® Copovidone has better plasticity than povidone when used as a tablet binder. It is less hygroscopic, more elastic, and better suited for film-forming applications than povidone. Copovidone is also used in cosmetics as a thickener, dispersant, lubricant, film-forming agent, and binder. It is widely used in the food, cosmetic, and pharmaceutical industries.
Liveida ® Copovidone is generally regarded as non-toxic. However, oral consumption of excessive quantities may cause stomach upset. It has not been shown to be skin sensitizing. Animal studies in rats and dogs do not show significant toxicity at high dietary levels.